Unit 3 — Endocrine system
Identify endocrine glands, their hormones and target organs. Explain hypothalamic control of the pituitary and compare membrane-receptor signalling with intracellular receptor action.
WACE Human Biology · Free preparation planner
Exam Predictors 2026
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Unit 3 — Central and peripheral nervous system
Compare the central and peripheral systems, sensory and motor pathways, and somatic and autonomic divisions. Relate CNS structures, protection, receptors, reflex pathways, action potentials and synapses to coordinated responses.
Unit 3 — Homeostasis
Explain feedback and tolerance limits through temperature, glucose, body-fluid and gas regulation. Integrate physiological and behavioural responses with nervous and endocrine control.
Unit 3 — Response to infection
Relate viral and bacterial transmission to external defences, inflammation and fever. Compare antibody-mediated and cell-mediated responses, active and passive immunity, vaccines, antibiotics and antivirals.
Unit 4 — Mutations
Explain gene and chromosome mutations arising from replication or division errors and mutagens. Relate new alleles to variation in genotype, phenotype and context-dependent survival.
Unit 4 — Gene pools
Represent populations through allele frequencies and examine changes caused by mutation, selection, drift, founder effects and gene flow. Explain differential reproductive success, isolation, speciation and the sickle-cell example.
Unit 4 — Evidence for evolution
Interpret phylogenetic relationships, comparative DNA and protein evidence, and the contribution of PCR, gel electrophoresis, sequencing and bioinformatics. Explain fossil-record limits and relative and absolute dating.
Unit 4 — Hominid evolutionary trends
Compare humans and other great apes using cerebral cortex, digits, locomotion, prognathism and dentition. Examine the seven named hominin fossil species and tool-culture trends for the four named Homo species.
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Official assessment material
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WACE Human Biology — revision plan
Human Biology ATAR Year 12 syllabus — for teaching from January 2024
Personal preparation priorities, not predicted exam questions, probabilities or grades.
Check current requirements and course options: https://senior-secondary.scsa.wa.edu.au/syllabus-and-support-materials/science/human-biology
Subject archive: https://atarmaxxing.com.au/subjects/wace-human-biology/papers